Research focus
Fat loss & metabolic research peptides
Compounds whose research concerns body weight, adiposity and metabolic and incretin pathways. Each compound below carries a score out of 100 combining the strength of its published research with the certificate evidence of the vendors that carry it — a score of evidence, never a claim that a compound is safe, effective or suitable for any purpose.
Browse by research focus
Showing 20 of 20 compounds — Compounds whose research concerns body weight, adiposity and metabolic and incretin pathways.
- S
Semaglutide
Metabolic92.4A GLP-1 receptor agonist peptide. Semaglutide is an approved prescription medicine in several jurisdictions under brand names held by its originator; material listed by the vendors in this index is sold as research-grade powder and is not the approved pharmaceutical product.
Fat loss8 vendors17 certificates99.7% mean purityTier S evidence · High popularity
- S
Tesamorelin
Metabolic92.2A stabilised analogue of growth-hormone-releasing hormone, approved to reduce excess visceral abdominal fat in a specific clinical population.
Fat lossMuscle & growth26 vendors37 certificates99.7% mean purityTier S evidence · High popularity
- A
MOTS-c
Metabolic84.5A mitochondrial-derived peptide studied for roles in cellular metabolism, insulin sensitivity and exercise physiology.
Fat lossLongevity23 vendors28 certificates99.6% mean purityTier A evidence · High popularity
- D
AOD-9604
Metabolic84A modified fragment of the C-terminus (residues 176–191) of human growth hormone, studied for effects on fat metabolism without the growth-promoting activity of the full-length hormone.
Fat loss20 vendors14 certificates99.5% mean purityTier D evidence · Established popularity
- S
Tirzepatide
Metabolic82.3A dual GIP and GLP-1 receptor agonist peptide. As with semaglutide, an approved pharmaceutical product exists; material listed by indexed vendors is research-grade powder and is not that product.
Fat loss12 vendors42 certificates99.8% mean purityTier S evidence · High popularity
- S
Cagrilintide
Metabolic77.8A long-acting analogue of the hormone amylin, studied for effects on appetite and body weight, frequently in combination with GLP-1 receptor agonists.
Fat loss15 vendors13 certificates99.4% mean purityTier S evidence · High popularity
- S
Retatrutide
Metabolic77An investigational triple receptor agonist peptide. No regulator has approved it as a medicine. It appears in the catalogs of several indexed vendors as research-grade powder.
Fat loss16 vendors61 certificates99.7% mean purityTier S evidence · High popularity
- D
5-Amino-1MQ
Metabolic69.6A small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), studied in the context of metabolism and adipose tissue. It is supplied as a research chemical rather than a peptide.
Fat lossLongevity17 vendors19 certificates99.7% mean purityTier D evidence · Established popularity
- C
BAM15
Metabolic38A mitochondrial protonophore (uncoupler) studied preclinically for effects on energy expenditure, obesity and metabolic disease.
Fat lossLongevity0 vendors0 certificatesTier C evidence · Niche popularity
- B
L-Carnitine
Metabolic38L-carnitine (levocarnitine), an amino-acid derivative central to the transport of fatty acids into mitochondria. It is available both as an approved medicine and as a dietary supplement and is extensively studied.
Fat loss0 vendors0 certificatesTier B evidence · Established popularity
- B
Metformin
Metabolic38A biguanide and one of the most widely prescribed oral medicines for type 2 diabetes. It is very extensively studied, including a large body of ageing and longevity research.
Fat lossLongevity0 vendors0 certificatesTier B evidence · High popularity
- C
Tesofensine
Metabolic38A triple monoamine-reuptake inhibitor investigated clinically for weight management. It is not an approved medicine.
Fat loss0 vendors0 certificatesTier C evidence · Niche popularity
- C
Survodutide
Metabolic32.3A dual GLP-1 and glucagon receptor agonist studied for obesity and metabolic (MASH) liver disease.
Fat loss2 vendors0 certificatesTier C evidence · High popularity
- C
ATX-304
Metabolic31.3A direct pan-AMPK activator (also known as O304), studied preclinically in metabolic and vascular models.
Fat lossLongevity0 vendors0 certificatesTier C evidence · Niche popularity
- D
SLU-PP-332
Metabolic25.2A synthetic pan-agonist of the estrogen-related receptors (ERRs), studied preclinically as an exercise-mimetic in models of metabolism and endurance.
Fat lossMuscle & growth1 vendors0 certificatesTier D evidence · Niche popularity
- D
HGH Fragment 176-191
Metabolic25.1A synthetic fragment corresponding to residues 176-191 of human growth hormone, studied in animal models for effects on lipid metabolism. The stabilised analogue AOD-9604 is tracked separately in this index.
Fat loss0 vendors0 certificatesTier D evidence · Niche popularity
- C
Orforglipron
Metabolic23.6An orally available, non-peptide small-molecule GLP-1 receptor agonist in late-stage clinical development for type 2 diabetes and obesity.
Fat loss0 vendors0 certificatesTier C evidence · Established popularity
- C
Mazdutide
Metabolic22.4A GLP-1 and glucagon receptor dual agonist peptide developed for obesity and metabolic disease. It has been approved in China and remains investigational elsewhere.
Fat loss0 vendors0 certificatesTier C evidence · Established popularity
- D
Eloralintide
Metabolic10.6A selective, long-acting amylin receptor agonist peptide (LY3841136) in clinical development for obesity and weight management.
Fat loss0 vendors0 certificatesTier D evidence · Niche popularity
- D
SLU-PP-915
Metabolic10.1An estrogen-related receptor (ERR) agonist from the same research programme as SLU-PP-332, studied preclinically in metabolism. The indexed literature is small and recent.
Fat loss0 vendors0 certificatesTier D evidence · Niche popularity