Tesofensine
MetabolicAlso known as NS2330
Evidence tier
Moderate published literature
56 publications over 19 years · trials not yet curated
- Researched since
- 2007
- Publications
- 56
- Mean purity
- —
- Vendors listing
- 0
No indexed vendor publishes certificate records for Tesofensine that this index could read yet, so no purity comparison is possible.
Score breakdown
The score has two halves: the research base — how long the compound has been studied and how much has been published — and the quality of the evidence the market produces for it, aggregated across every vendor that carries it: assayed purity, lot-to-lot consistency, readable third-party certificates and those vendors’ review record. It measures the evidence base, not the merits or safety of the substance.
Studied since 2007 — 19 years of published research
How long the compound has been studied. Fifteen years or more of published literature earns full marks; a newer compound earns less.
56 publications indexed in PubMed
The volume of published literature located. Full marks at fifty or more publications.
No certificate records indexed yet — nothing recorded yet
Average assayed purity on the certificates published by vendors that carry this compound. Full marks at 99.5%+, nothing at 95% or below.
No certificate records indexed yet — nothing recorded yet
How tightly assayed purity and labeled-versus-actual mass hold across different lots. Rewards reproducible manufacturing.
No vendor testing policy recorded yet — nothing recorded yet
Whether the vendors carrying this compound publish per-lot certificates anyone can read without an account.
No certificate records indexed yet — nothing recorded yet
Share of certificates issued by a recognised third-party testing lab rather than an unnamed or self-named one.
What is Tesofensine?
A triple monoamine-reuptake inhibitor investigated clinically for weight management. It is not an approved medicine.
Studied in published research for obesity and weight management.
Regulatory status
Tesofensine is an investigational compound in clinical development and is not an approved medicine in the United States, United Kingdom or European Union. Products listed here are labeled by their vendors for laboratory research use only.
What the research examines
The areas of published research this compound appears in. These describe what the literature has studied — never a claim of benefit, effect or suitability for any use.
Published research
PepIndex records the size and shape of the published research footprint only. It does not evaluate or summarise clinical significance, does not describe administration, and nothing here is a claim of safety or efficacy.
- Tesofensine, a monoamine reuptake inhibitor for the treatment of obesity — Current opinion in investigational drugs (London, England : 2000) (2009)
Peer-reviewed article indexed in PubMed, published in Current opinion in investigational drugs (London, England : 2000) (2009).
- Tesofensine, a novel antiobesity drug, silences GABAergic hypothalamic neurons — PloS one (2024)
Peer-reviewed article indexed in PubMed, published in PloS one (2024).
- Weight loss produced by tesofensine in patients with Parkinson's or Alzheimer's disease — Obesity (Silver Spring, Md.) (2008)
Peer-reviewed article indexed in PubMed, published in Obesity (Silver Spring, Md.) (2008).
- Tesofensine and weight loss — Lancet (London, England) (2009)
Peer-reviewed article indexed in PubMed, published in Lancet (London, England) (2009).
- Tesofensine and weight loss — Lancet (London, England) (2009)
Peer-reviewed article indexed in PubMed, published in Lancet (London, England) (2009).
- Tesofensine, a novel triple monoamine reuptake inhibitor, induces appetite suppression by indirect stimulation of alpha1 adrenoceptor and dopamine D1 receptor pathways in the diet-induced obese rat — Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2010)
Peer-reviewed article indexed in PubMed, published in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2010).
PepIndex describes what literature exists. We do not interpret it, assess clinical significance, or publish quantities, protocols or instructions for use.
Vendor comparison
| Vendor | Score here | Price / mg | Certificates | Mean purity | Label deviation | Get it |
|---|
Certificate records
No certificate records are indexed. Either none are published, or those published could not be read without an account.