Peptide directory

Vasoactive intestinal peptide, a 28–amino-acid signalling peptide with roles in vasodilation, secretion and inflammation. Its related drug is known as aviptadil.

Tier S evidence · Niche popularity

A growth-hormone-releasing hexapeptide and ghrelin-receptor agonist studied for stimulating growth hormone secretion.

Tier B evidence · Established popularity

A tripeptide of glutamate, cysteine and glycine that is the body’s principal intracellular antioxidant, supplied for research and compounding in its reduced form.

Tier S evidence · Established popularity

A 28–amino-acid peptide derived from the thymus gland, studied for effects on immune modulation. An approved form is marketed in some countries as thymalfasin.

Tier S evidence · Established popularity

A coenzyme present in all living cells, sold by research chemical vendors as a lyophilised powder. It is a nucleotide rather than a peptide, and is included here because it appears in the catalogs of vendors in this index.

Tier S evidence · High popularity

A synthetic analogue of alpha-melanocyte-stimulating hormone that stimulates melanin production, studied in relation to skin pigmentation. Its approved form is known as afamelanotide.

Tier S evidence · Established popularity

A melanocortin receptor agonist derived from melanotan II, studied for effects on sexual arousal. Its approved form is known as bremelanotide.

Tier A evidence · High popularity

A synthetic analogue of alpha-melanocyte stimulating hormone. It has been the subject of regulatory warnings in several countries regarding unlicensed sale.

Tier B evidence · High popularity

A mitochondria-targeted tetrapeptide (also known as elamipretide) studied for its effects on mitochondrial function and cellular energy.

Tier B evidence · Established popularity

A synthetic peptide derived from a fragment of adrenocorticotropic hormone (ACTH 4-10), studied in relation to cognition and neuroprotection. It was developed in Russia.

Tier A evidence · High popularity

An eleven–amino-acid peptide derived from the structure of erythropoietin, designed to engage tissue-protective signalling without the red-blood-cell effects of erythropoietin.

Tier S evidence · Niche popularity

A synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the pineal peptide epithalamin, studied in relation to telomerase activity and ageing.

Tier B evidence · Established popularity

A synthetic pentapeptide that acts as a growth hormone secretagogue in published preclinical work. Supplied as a lyophilised powder.

Tier A evidence · High popularity

Delta sleep-inducing peptide, a nine–amino-acid peptide first isolated from cerebral blood, studied in relation to sleep regulation and stress responses.

Tier A evidence · Established popularity

A synthetic peptide corresponding to the first 29 amino acids of growth-hormone-releasing hormone, which stimulates the pituitary gland to release growth hormone.

Tier A evidence · Established popularity

A GLP-1 receptor agonist peptide. Semaglutide is an approved prescription medicine in several jurisdictions under brand names held by its originator; material listed by the vendors in this index is sold as research-grade powder and is not the approved pharmaceutical product.

Tier S evidence · High popularity

A synthetic growth-hormone-releasing hexapeptide studied for growth hormone secretion and cardiovascular effects.

Tier B evidence · Established popularity

A stabilised analogue of growth-hormone-releasing hormone, approved to reduce excess visceral abdominal fat in a specific clinical population.

Tier S evidence · High popularity

A synthetic heptapeptide based on the immune peptide tuftsin, studied in relation to anxiety and cognition. It was developed in Russia.

Tier A evidence · High popularity

A synthetic peptide of fifteen amino acids, derived from a sequence identified in human gastric juice. It is supplied as a lyophilised powder and is one of the most widely listed compounds across the vendors in this index.

Tier C evidence · High popularity

A copper-binding tripeptide found naturally in human plasma. It appears widely in topical cosmetic formulations and is also listed by research chemical vendors as a lyophilised powder.

Tier A evidence · High popularity

A peptide encoded by the KISS1 gene that signals through the KISS1 receptor to regulate release of gonadotropin-releasing hormone, central to reproductive endocrinology.

Tier A evidence · Established popularity

A modified, longer-acting analogue of insulin-like growth factor 1, altered to extend its half-life and reduce binding to carrier proteins. It is a common cell-culture reagent.

Tier B evidence · Established popularity

A synthetic analogue of growth hormone releasing hormone. Two distinct forms circulate under similar names — with and without a drug affinity complex — and vendors are not consistent about which they list. This index records the form named on the certificate rather than the form named in the product title.

Tier A evidence · High popularity

A synthetic peptide fragment related to the naturally occurring protein thymosin beta-4. Supplied as a lyophilised powder.

Tier A evidence · High popularity

A mitochondrial-derived peptide studied for roles in cellular metabolism, insulin sensitivity and exercise physiology.

Tier A evidence · High popularity

A modified fragment of the C-terminus (residues 176–191) of human growth hormone, studied for effects on fat metabolism without the growth-promoting activity of the full-length hormone.

Tier D evidence · Established popularity

A dual GIP and GLP-1 receptor agonist peptide. As with semaglutide, an approved pharmaceutical product exists; material listed by indexed vendors is research-grade powder and is not that product.

Tier S evidence · High popularity

A tripeptide (lysine-proline-valine) corresponding to the C-terminal fragment of alpha-melanocyte-stimulating hormone, studied for anti-inflammatory signalling.

Tier D evidence · Established popularity

A long-acting analogue of the hormone amylin, studied for effects on appetite and body weight, frequently in combination with GLP-1 receptor agonists.

Tier S evidence · High popularity

An investigational triple receptor agonist peptide. No regulator has approved it as a medicine. It appears in the catalogs of several indexed vendors as research-grade powder.

Tier S evidence · High popularity

A synthetic peptide studied as a senolytic — a compound aimed at clearing senescent cells — in preclinical ageing models.

Tier D evidence · Niche popularity

A small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), studied in the context of metabolism and adipose tissue. It is supplied as a research chemical rather than a peptide.

Tier D evidence · Established popularity

A human cathelicidin-derived antimicrobial peptide studied for antimicrobial activity, immune modulation and wound healing.

Tier B evidence · Established popularity

An eight–amino-acid peptide extension of the cosmetic peptide argireline, studied topically in relation to the appearance of expression lines.

Tier B evidence · Niche popularity

A peptide preparation derived from porcine brain tissue, studied in stroke, dementia and traumatic brain injury. It is approved as a medicine in some countries but not in the United States.

Tier B evidence · Established popularity

An isoform of follistatin, an endogenous antagonist of myostatin and related TGF-beta ligands. Its published literature is predominantly preclinical and concerns muscle, fibrosis and reproductive biology.

Tier B evidence · Niche popularity

Larazotide acetate, a synthetic octapeptide studied as a tight-junction regulator (a zonulin antagonist) and investigated clinically in coeliac disease.

Tier C evidence · Niche popularity

A mitochondrial-derived peptide studied for cytoprotective and neuroprotective effects in models of ageing and metabolism.

Tier B evidence · Niche popularity

A nine-amino-acid neuropeptide hormone produced in the hypothalamus. It is an approved medicine and is one of the most heavily studied peptides in physiology and behavioural neuroscience.

Tier B evidence · Established popularity

A growth-hormone-releasing peptide (also known as pralmorelin) studied for stimulating growth hormone secretion.

Tier B evidence · Established popularity

A short synthetic peptide (Glu-Asp-Arg) from the Khavinson peptide-bioregulator research programme, studied preclinically in models of oxidative stress and neuroprotection.

Tier D evidence · Niche popularity

A copper-binding tripeptide (alanine-histidine-lysine) in the copper-peptide class, studied for effects on hair follicles and used as a cosmetic ingredient.

Tier D evidence · Niche popularity

A mitochondrial protonophore (uncoupler) studied preclinically for effects on energy expenditure, obesity and metabolic disease.

Tier C evidence · Niche popularity

Human chorionic gonadotropin, a glycoprotein hormone with luteinising-hormone-like activity. It is an approved prescription medicine used in reproductive endocrinology and is listed by vendors here as a research material.

Tier B evidence · Established popularity

Recombinant human growth hormone (somatropin), a 191-amino-acid protein identical to the pituitary hormone. It is one of the most extensively studied compounds in endocrinology and is supplied by the vendors in this index as a research material.

Tier B evidence · High popularity

L-carnitine (levocarnitine), an amino-acid derivative central to the transport of fatty acids into mitochondria. It is available both as an approved medicine and as a dietary supplement and is extensively studied.

Tier B evidence · Established popularity

Recombinant human insulin-like growth factor-1 (mecasermin). It is an approved prescription medicine for severe primary IGF-1 deficiency and is listed by vendors here as a research material.

Tier B evidence · Niche popularity

Human menopausal gonadotropin (hMG), a purified preparation carrying follicle-stimulating and luteinising hormone activity. It is an approved fertility medicine.

Tier B evidence · Niche popularity

A biguanide and one of the most widely prescribed oral medicines for type 2 diabetes. It is very extensively studied, including a large body of ageing and longevity research.

Tier B evidence · High popularity

Methylene blue (methylthioninium chloride), a synthetic phenothiazine dye and redox-active compound with a research history stretching back to the nineteenth century. It is an approved medicine for specific indications.

Tier B evidence · Established popularity

Rapamycin (sirolimus), a macrolide inhibitor of the mTOR pathway. It is an approved prescription medicine and one of the most-studied compounds in ageing and longevity research.

Tier B evidence · High popularity

A triple monoamine-reuptake inhibitor investigated clinically for weight management. It is not an approved medicine.

Tier C evidence · Niche popularity

A polypeptide preparation extracted from thymus tissue, studied for immunomodulatory effects. It has clinical use in some countries but is not approved in the United States.

Tier B evidence · Niche popularity

A synthetic decapeptide agonist of gonadotropin-releasing hormone (GnRH). It is an approved prescription medicine used in endocrinology and oncology.

Tier B evidence · Established popularity

A synthetic dipeptide (Lys-Glu) from the Khavinson peptide-bioregulator research programme, studied preclinically for effects on gene expression, immune function and ageing in animal models.

Tier C evidence · Niche popularity

A small peptide derivative studied for effects on synaptic connections and neurotrophic signalling in models of cognition. It is supplied as a research compound.

Tier A evidence · Niche popularity

A synthetic 34-amino-acid analogue of parathyroid-hormone-related protein (PTHrP). It is an approved prescription medicine for osteoporosis.

Tier B evidence · Niche popularity

A dual GLP-1 and glucagon receptor agonist studied for obesity and metabolic (MASH) liver disease.

Tier C evidence · High popularity

A direct pan-AMPK activator (also known as O304), studied preclinically in metabolic and vascular models.

Tier C evidence · Niche popularity

A shortened synthetic analogue of spadin, studied preclinically as a TREK-1 potassium-channel inhibitor with antidepressant-like activity in animal models. The indexed literature under this exact name is very limited.

Tier D evidence · Niche popularity

A synthetic pan-agonist of the estrogen-related receptors (ERRs), studied preclinically as an exercise-mimetic in models of metabolism and endurance.

Tier D evidence · Niche popularity

A synthetic fragment corresponding to residues 176-191 of human growth hormone, studied in animal models for effects on lipid metabolism. The stabilised analogue AOD-9604 is tracked separately in this index.

Tier D evidence · Niche popularity

An orally available, non-peptide small-molecule GLP-1 receptor agonist in late-stage clinical development for type 2 diabetes and obesity.

Tier C evidence · Established popularity

A GLP-1 and glucagon receptor dual agonist peptide developed for obesity and metabolic disease. It has been approved in China and remains investigational elsewhere.

Tier C evidence · Established popularity

A selective, long-acting amylin receptor agonist peptide (LY3841136) in clinical development for obesity and weight management.

Tier D evidence · Niche popularity

An estrogen-related receptor (ERR) agonist from the same research programme as SLU-PP-332, studied preclinically in metabolism. The indexed literature is small and recent.

Tier D evidence · Niche popularity