Humanin
OtherAlso known as HN, MTRNR2
Evidence tier
Substantial published literature
495 publications over 56 years · trials not yet curated
- Researched since
- 1970
- Publications
- 495
- Mean purity
- —
- Vendors listing
- 1
No indexed vendor publishes certificate records for Humanin that this index could read yet, so no purity comparison is possible.
Score breakdown
The score has two halves: the research base — how long the compound has been studied and how much has been published — and the quality of the evidence the market produces for it, aggregated across every vendor that carries it: assayed purity, lot-to-lot consistency, readable third-party certificates and those vendors’ review record. It measures the evidence base, not the merits or safety of the substance.
Studied since 1970 — 56 years of published research
How long the compound has been studied. Fifteen years or more of published literature earns full marks; a newer compound earns less.
495 publications indexed in PubMed
The volume of published literature located. Full marks at fifty or more publications.
No certificate records indexed yet — nothing recorded yet
Average assayed purity on the certificates published by vendors that carry this compound. Full marks at 99.5%+, nothing at 95% or below.
No certificate records indexed yet — nothing recorded yet
How tightly assayed purity and labeled-versus-actual mass hold across different lots. Rewards reproducible manufacturing.
1 of 1 listing vendor publish an accessible certificate policy
Whether the vendors carrying this compound publish per-lot certificates anyone can read without an account.
No certificate records indexed yet — nothing recorded yet
Share of certificates issued by a recognised third-party testing lab rather than an unnamed or self-named one.
What is Humanin?
A mitochondrial-derived peptide studied for cytoprotective and neuroprotective effects in models of ageing and metabolism.
Studied in published research for neuroprotection, metabolism and ageing.
Regulatory status
Labeled by vendors for laboratory research use only. Not approved as a medicine in the United States, United Kingdom, or European Union.
What the research examines
The areas of published research this compound appears in. These describe what the literature has studied — never a claim of benefit, effect or suitability for any use.
Published research
Published work is largely preclinical, in cell and animal models. PepIndex does not evaluate clinical significance and does not describe administration.
- Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseases — Life sciences (2021)
Peer-reviewed article indexed in PubMed, published in Life sciences (2021).
- Role of humanin, a mitochondrial-derived peptide, in cardiovascular disorders — Archives of cardiovascular diseases (2020)
Peer-reviewed article indexed in PubMed, published in Archives of cardiovascular diseases (2020).
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance — Cell metabolism (2015)
Peer-reviewed article indexed in PubMed, published in Cell metabolism (2015).
- Humanin: A mitochondria-derived peptide with emerging properties — Annales de cardiologie et d'angeiologie (2020)
Peer-reviewed article indexed in PubMed, published in Annales de cardiologie et d'angeiologie (2020).
- Mitochondrial-derived peptide humanin as therapeutic target in cancer and degenerative diseases — Expert opinion on therapeutic targets (2019)
Peer-reviewed article indexed in PubMed, published in Expert opinion on therapeutic targets (2019).
- The emerging role of mitochondrial derived peptide humanin in the testis — Biochimica et biophysica acta. General subjects (2021)
Peer-reviewed article indexed in PubMed, published in Biochimica et biophysica acta. General subjects (2021).
- Mitochondrial stress and mitokines in aging — Aging cell (2023)
Peer-reviewed article indexed in PubMed, published in Aging cell (2023).
- An evidence of Humanin-like peptide and Humanin mediated cryosurvival of spermatozoa in buffalo bulls — Theriogenology (2022)
Peer-reviewed article indexed in PubMed, published in Theriogenology (2022).
PepIndex describes what literature exists. We do not interpret it, assess clinical significance, or publish quantities, protocols or instructions for use.
Vendor comparison
| Vendor | Score here | Price / mg | Certificates | Mean purity | Label deviation | Get it |
|---|---|---|---|---|---|---|
| American PeptidesISO/IEC 17025 | 86.5100% | $15.00 (100%) | 0 | — | — |
Certificate records
No certificate records are indexed. Either none are published, or those published could not be read without an account.