Research focus
Longevity & cellular health research peptides
Research concerns mitochondrial function, cellular senescence, NAD⁺ biology and ageing. Each compound below carries a score out of 100 combining the strength of its published research with the certificate evidence of the vendors that carry it — a score of evidence, never a claim that a compound is safe, effective or suitable for any purpose.
Browse by research focus
Showing 18 of 18 compounds — Research concerns mitochondrial function, cellular senescence, NAD⁺ biology and ageing.
- S
Glutathione
Other94.7A tripeptide of glutamate, cysteine and glycine that is the body’s principal intracellular antioxidant, supplied for research and compounding in its reduced form.
LongevitySkin & hair16 vendors15 certificates99.6% mean purityTier S evidence · Established popularity
- S
NAD+
Metabolic94A coenzyme present in all living cells, sold by research chemical vendors as a lyophilised powder. It is a nucleotide rather than a peptide, and is included here because it appears in the catalogs of vendors in this index.
Longevity18 vendors18 certificates99.8% mean purityTier S evidence · High popularity
- B
SS-31
Tissue & recovery93.7A mitochondria-targeted tetrapeptide (also known as elamipretide) studied for its effects on mitochondrial function and cellular energy.
LongevityHealing15 vendors12 certificates99.7% mean purityTier B evidence · Established popularity
- B
Epithalon
Other93.1A synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the pineal peptide epithalamin, studied in relation to telomerase activity and ageing.
Longevity23 vendors13 certificates99.5% mean purityTier B evidence · Established popularity
- A
MOTS-c
Metabolic84.5A mitochondrial-derived peptide studied for roles in cellular metabolism, insulin sensitivity and exercise physiology.
Fat lossLongevity23 vendors28 certificates99.6% mean purityTier A evidence · High popularity
- D
FOXO4-DRI
Other70.3A synthetic peptide studied as a senolytic — a compound aimed at clearing senescent cells — in preclinical ageing models.
Longevity3 vendors1 certificates99.1% mean purityTier D evidence · Niche popularity
- D
5-Amino-1MQ
Metabolic69.6A small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), studied in the context of metabolism and adipose tissue. It is supplied as a research chemical rather than a peptide.
Fat lossLongevity17 vendors19 certificates99.7% mean purityTier D evidence · Established popularity
- B
Humanin
Other50.3A mitochondrial-derived peptide studied for cytoprotective and neuroprotective effects in models of ageing and metabolism.
Longevity1 vendors0 certificatesTier B evidence · Niche popularity
- D
Pinealon
Other42.6A short synthetic peptide (Glu-Asp-Arg) from the Khavinson peptide-bioregulator research programme, studied preclinically in models of oxidative stress and neuroprotection.
LongevityCognitive5 vendors0 certificatesTier D evidence · Niche popularity
- C
BAM15
Metabolic38A mitochondrial protonophore (uncoupler) studied preclinically for effects on energy expenditure, obesity and metabolic disease.
Fat lossLongevity0 vendors0 certificatesTier C evidence · Niche popularity
- B
HGH (Somatropin)
Tissue & recovery38Recombinant human growth hormone (somatropin), a 191-amino-acid protein identical to the pituitary hormone. It is one of the most extensively studied compounds in endocrinology and is supplied by the vendors in this index as a research material.
Muscle & growthLongevity0 vendors0 certificatesTier B evidence · High popularity
- B
Metformin
Metabolic38A biguanide and one of the most widely prescribed oral medicines for type 2 diabetes. It is very extensively studied, including a large body of ageing and longevity research.
Fat lossLongevity0 vendors0 certificatesTier B evidence · High popularity
- B
Methylene Blue
Other38Methylene blue (methylthioninium chloride), a synthetic phenothiazine dye and redox-active compound with a research history stretching back to the nineteenth century. It is an approved medicine for specific indications.
CognitiveLongevity0 vendors0 certificatesTier B evidence · Established popularity
- B
Rapamycin (Sirolimus)
Other38Rapamycin (sirolimus), a macrolide inhibitor of the mTOR pathway. It is an approved prescription medicine and one of the most-studied compounds in ageing and longevity research.
Longevity0 vendors0 certificatesTier B evidence · High popularity
- B
Thymalin
Tissue & recovery38A polypeptide preparation extracted from thymus tissue, studied for immunomodulatory effects. It has clinical use in some countries but is not approved in the United States.
Gut & immuneLongevity0 vendors0 certificatesTier B evidence · Niche popularity
- C
Vilon
Other38A synthetic dipeptide (Lys-Glu) from the Khavinson peptide-bioregulator research programme, studied preclinically for effects on gene expression, immune function and ageing in animal models.
LongevityGut & immune0 vendors0 certificatesTier C evidence · Niche popularity
- B
Abaloparatide
Other33.2A synthetic 34-amino-acid analogue of parathyroid-hormone-related protein (PTHrP). It is an approved prescription medicine for osteoporosis.
LongevityHormonal0 vendors0 certificatesTier B evidence · Niche popularity
- C
ATX-304
Metabolic31.3A direct pan-AMPK activator (also known as O304), studied preclinically in metabolic and vascular models.
Fat lossLongevity0 vendors0 certificatesTier C evidence · Niche popularity