Vendor comparison · 2026
Epithalon vendors: 26 compared on COAs and price
OtherAlso known as Epitalon, Epithalone, AEDG peptide
Evidence tier
Some human data
1 human trial
- Vendors carrying it
- 26
- 24 with a listed price
- Vendors with checkable COAs
- 10
- 11 publish any certificate
- Lots tested
- 16
- 15 naming a checkable lab
- Independent assays
- 0
- none on file yet
- Newest assay
- 23 Sept 2026
- oldest 28 Apr 2025
- Laboratories named
- 7
- most often Freedom Diagnostics Testing
- Median label gap
- 6.0%
- 44% of lots within 5% of label
- Median purity
- 99.60%
- 16 of 16 lots at 99% or above
- Lowest price per mg
- $1.18
- peer median $4.10
- Publications located
- 142
- researched since 2000
Source: PepIndex, an independent index of research-peptide vendors. No vendor can pay for a rank, every score is computed by a published formula, and every figure links to the document it was read from.
Next Gen Peptides has the most checkable Epithalon testing in this index: 3 lots assayed by ILS Laboratories, the newest on 23 Sept 2026. The lowest listed price is $1.18 per mg at True Research Labs, against a peer median of $4.10. 26 vendors carrying Epithalon are compared below. 10 publish at least one certificate naming a checkable laboratory, 16 lot records are on file, and none is an independently commissioned assay. Figures are PepIndex's own: it is an independent index of research-peptide vendors, no vendor can pay for a rank, and each figure links to the certificate it was read from.
Every vendor carrying Epithalon
| # | Vendor | Score here | Price / mg | Lots | Newest test | Laboratory | Mean purity | Label gap | Reports |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Next Gen PeptidesISO/IEC 17025 | 93.697% | — | 3 / 3 | ILS Laboratories | 99.2% | 2.8% | ||
| 2 | Amino ClubISO/IEC 17025Age-gated COAs | 90.998% | $3.00 (73%) | 0 | — | — | — | — | |
| 3 | Ascend ScienceISO/IEC 17025 | 87.694% | $3.85 (94%) | 0 | — | — | — | — | |
| 4 | Modern AminosISO/IEC 17025COAs need an account | 87.297% | $2.80 (68%) | 0 | — | — | — | — | no reportVisit site |
| 5 | PeptidePlugs | 84.894% | $4.00 (98%) | 3 / 3 | Freedom Diagnostics Testing | 99.7% | 12.9% | ||
| 6 | Simple Peptide | 8392% | $3.30 (81%) | 1 / 1 | Freedom Diagnostics Testing | 99.9% | 6.4% | ||
| 7 | Hydro Research PeptidesISO/IEC 17025 | 8189% | $3.60 (88%) | 0 / 1 | Not named | 99.6% | 0.0% | ||
| 8 | Bench Grade Peptides | 80.289% | $4.20 (102%) | 2 / 2 | AV Analytics, Freedom Diagnostics Testing | 99.9% | 4.5% | ||
| 9 | One Aminos | 79.889% | $4.50 (110%) | 1 / 1 | United Laboratories | 99.6% | 26.4% | ||
| 10 | Ascension Peptides | 7789% | $5.00 (122%) | 1 / 1 | Kovera Labs | 99.3% | 3.6% | ||
| 11 | Evo Labs Research | 76.787% | $3.20 (78%) | 0 | — | — | — | — | no reportVisit site |
| 12 | NeuroLabs Research | 74.591% | $5.40 (132%) | 0 | — | — | — | — | no reportVisit site |
| 13 | Evolve Peptides | 72.468% | $2.60 (63%) | 0 | — | — | — | — | no reportVisit site |
| 14 | CuroISO/IEC 17025 | 72.297% | $6.50 (159%) | 1 / 1 | BTLabs | 99.5% | 44.0% | ||
| 15 | True Research Labs | 7168% | $1.18 (30%) | 0 | — | — | — | — | no reportVisit site |
| 16 | GenX Peptides | 68.769% | $3.50 (85%) | 0 | — | — | — | — | no reportVisit site |
| 17 | Koi PeptidesAge-gated COAs | 67.192% | $6.00 (146%) | 1 / 1 | Freedom Diagnostics Testing | 99.1% | 3.5% | ||
| 18 | Good Science Bio | 65.571% | $4.50 (110%) | 0 | — | — | — | — | no reportVisit site |
| 19 | Protide HealthAge-gated COAs | 65.192% | $7.50 (183%) | 0 | — | — | — | — | no reportVisit site |
| 20 | Eternal Peptides | 64.963% | $3.50 (85%) | 0 | — | — | — | — | no reportVisit site |
| 21 | BioLongevity Labs | 64.372% | $4.75 (116%) | 0 | — | — | — | — | no reportVisit site |
| 22 | Biotech Peptides | 63.860% | $3.76 (92%) | 0 | — | — | — | — | no reportVisit site |
| 23 | Licensed Peptides | 60.687% | $9.20 (224%) | 1 / 1 | Vanguard Laboratory | 99.8% | 9.4% | ||
| 24 | Vertex Labs | 56.172% | — | 1 / 1 | Freedom Diagnostics Testing | 99.3% | 6.7% | ||
| 25 | Improved Peptides | 55.487% | $6.50 (159%) | 0 | — | — | — | — | no reportVisit site |
| 26 | Mile High Compounds | 47.591% | $12.00 (250%) | 0 | — | — | — | — | no reportVisit site |
Independent assays
No independently commissioned assay of Epithalon is on file. All 16 records below were published by the vendor that sells the product, naming the laboratory shown. PepIndex does not yet commission its own assays, so nothing on this page establishes what is in a vial beyond the vendor’s own certificate. A record moves into this section the moment an assay commissioned by anyone other than the seller is indexed.
What the certificates show
16 of 16 lots at 99% or above; median 99.60%.
| Range | lots |
|---|---|
| <95% | 0 |
| 95–97% | 0 |
| 97–98% | 0 |
| 98–99% | 0 |
| 99–99.5% | 5 |
| ≥99.5% | 11 |
44% of lots within 5% of the labelled mass; median gap 6.0%.
| Range | lots |
|---|---|
| ≤2% | 2 |
| 2–5% | 5 |
| 5–10% | 5 |
| 10–20% | 1 |
| >20% | 3 |
24 vendors, $1.18 to $12.00; median $4.10.
| Range | vendors |
|---|---|
| $0–$5.00 | 16 |
| $5.00–$10.00 | 7 |
| $10.00–$15.00 | 1 |
Purity and mass are read from each certificate as published; the label gap is |labeled − assayed| ÷ labeled. Every value behind these bars is in the certificate table below.
Laboratories used
| Laboratory | Lots | Vendors | Share | Verify |
|---|---|---|---|---|
| Freedom Diagnostics TestingUS | 7 | 5 | 44% | Public lookup |
| ILS LaboratoriesUS | 3 | 1 | 19% | Public lookup |
| AV Analytics | 1 | 1 | 6% | No public lookup found |
| BTLabs | 1 | 1 | 6% | No public lookup found |
| Kovera Labs | 1 | 1 | 6% | No public lookup found |
| United LaboratoriesIN | 1 | 1 | 6% | Public lookup |
| Vanguard LaboratoryUS | 1 | 1 | 6% | No public lookup found |
1 further record namesno checkable laboratory (a placeholder, a signature line or the vendor’s own name). It is listed in the certificate table but not counted as third-party testing.
Every certificate record
Score breakdown
The score has two halves: the research base — how long the compound has been studied and how much has been published — and the quality of the evidence the market produces for it, aggregated across every vendor that carries it: assayed purity, lot-to-lot consistency, readable third-party certificates and those vendors’ review record. It measures the evidence base, not the merits or safety of the substance.
Studied since 2000 — 26 years of published research
How long the compound has been studied. Fifteen years or more of published literature earns full marks; a newer compound earns less.
142 publications indexed in PubMed
The volume of published literature located. Full marks at fifty or more publications.
Mean assayed purity 99.5% across 16 certificates
Average assayed purity on the certificates published by vendors that carry this compound. Full marks at 99.5%+, nothing at 95% or below.
±0.28 pts purity across lots, mean label deviation 9.8%
How tightly assayed purity and labeled-versus-actual mass hold across different lots. Rewards reproducible manufacturing.
26 of 26 listing vendors publish an accessible certificate policy
Whether the vendors carrying this compound publish per-lot certificates anyone can read without an account.
15 of 16 certificates from a recognised independent lab
Share of certificates issued by a recognised third-party testing lab rather than an unnamed or self-named one.
What is Epithalon?
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the pineal peptide epithalamin, studied in relation to telomerase activity and ageing.
Studied in published research for ageing, telomere biology and circadian regulation.
Regulatory status
Labeled by vendors for laboratory research use only. Not approved as a medicine in the United States, United Kingdom, or European Union.
What the research examines
The areas of published research this compound appears in. These describe what the literature has studied — never a claim of benefit, effect or suitability for any use.
Published research
Published work includes cell, animal and small human studies, much of it from a single research group. PepIndex does not evaluate clinical significance and does not describe administration.
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions — Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews (2026)
Peer-reviewed article indexed in PubMed, published in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews (2026).
- Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties — International journal of molecular sciences (2025)
Peer-reviewed article indexed in PubMed, published in International journal of molecular sciences (2025).
- Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity — Biogerontology (2025)
Peer-reviewed article indexed in PubMed, published in Biogerontology (2025).
- Peptides and Ageing — Neuro endocrinology letters (2002)
Peer-reviewed article indexed in PubMed, published in Neuro endocrinology letters (2002).
- Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro — Aging (2022)
Peer-reviewed article indexed in PubMed, published in Aging (2022).
- The Antioxidant Tetrapeptide Epitalon Enhances Delayed Wound Healing in an in Vitro Model of Diabetic Retinopathy — Stem cell reviews and reports (2025)
Peer-reviewed article indexed in PubMed, published in Stem cell reviews and reports (2025).
- Correction: Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity — Biogerontology (2025)
Peer-reviewed article indexed in PubMed, published in Biogerontology (2025).
- Studies of the effects of Vilon and Epithalon on gene expression in mouse heart using DNA-microarray technology — Bulletin of experimental biology and medicine (2002)
Peer-reviewed article indexed in PubMed, published in Bulletin of experimental biology and medicine (2002).
Indexed studies1 human-evidence of 1
- Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa — Human — controlled trial, 2002
We have studied the effect of tetrapeptide Epitalon (Ala-Glu-Asp-Gly) on the course of congenital pigmented degeneration of the retina. The application of Epitalon in Campbell rats is found to intensify the bioelectric and functional activity of the retina due to the preservation of its morphological structure. Epitalon therapy in patients with degenerative retinal lesions results in a positive clinical effect in 90% of the cases. The analysis of Epitalon effects suggests tha…
Evidence digest
What the research on Epithalon actually shows
The indexed literature on Epithalon includes human clinical or observational records (1 human-clinical or observational record). This digest describes the shape of that evidence and links the records behind it. It does not judge whether Epithalon is safe or effective for any purpose, and nothing here is medical advice — the material sold by the vendors in this index is labeled for laboratory research use only.
3 things the literature does not establish →
PepIndex describes what literature exists. We do not interpret it, assess clinical significance, or publish quantities, protocols or instructions for use.