Human — controlled trial

Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin

To evaluate the role of skin care products that contain a copper tripeptide complex, glycyl-l-histidyl-l-lysine-Cu(2+) (GHK-Cu), in treating carbon dioxide (CO(2)) laser-resurfaced skin. Patients meeting the inclusion criteria underwent circumoral skin resurfacing using a CO(2) laser at standard settings. Patients were then randomized to receive posttreatment skin regimens with or without GHK-Cu. Evaluations for erythema throughout the posttreatment period were performed usin…

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GHK-Cu
What the research on GHK-Cu actually shows
The indexed literature on GHK-Cu includes human clinical or observational records (3 human-clinical or observational records, 1 in-vitro record). This digest describes the shape of that evidence and links the records behind it. It does not judge whether GHK-Cu is safe or effective for any purpose, and nothing here is medical advice — the material sold by the vendors in this index is labeled for laboratory research use only.

Compounds examined

GHK-Cu

Study records state what a paper reported. PepIndex does not interpret findings, assess clinical significance, or restate results in language implying an application not present in the source. Last reviewed 23 Jul 2026.