Evidence digest
What the research on Kisspeptin actually shows
The indexed literature on Kisspeptin includes human clinical or observational records (4 human-clinical or observational records). This digest describes the shape of that evidence and links the records behind it. It does not judge whether Kisspeptin is safe or effective for any purpose, and nothing here is medical advice — the material sold by the vendors in this index is labeled for laboratory research use only.
Updated 25 Aug 2026 · 4 studies indexed · 4 human · compound record
- Studies indexed
- 4
- Human evidence
- 4
- Preclinical only
- 0
What is and is not established
What the literature supports
- Human clinical or observational records are indexed for Kisspeptin (4).
- Published research is indexed back to 1997, with roughly 3,829 PubMed records located.
- It is listed by one or more vendors tracked in this index.
What is NOT established
- This index does not evaluate whether Kisspeptin is safe or effective for any use.
- Material sold by the vendors indexed here is labeled for laboratory research use only and is not a regulator-approved medicine in that form.
- No dosing, protocol or human-use guidance is provided or implied anywhere in this index.
Studies indexed
2 systematic review · 1 human — controlled trial · 1 meta-analysis
| Study | Evidence type | Model | n | What it reported | Source |
|---|---|---|---|---|---|
| Kisspeptin as a predictor of miscarriage: a systematic reviewThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medici · 2023 | Systematic review | Not recorded | — | A highly accurate serum marker for predicting viable pregnancy needs to be developed. Recent studies have demonstrated that kisspeptin is a potential biomarker for this purpose. This systematic review evaluated the available data in the literature on the role of kisspeptin as a miscarriage biomarker. A literature search was conducted in the PubMed/Medline, Embase, Web of Science, and Scopus databases using the following keywords: (kisspeptin) AND (miscarriage OR pregnancy los… | PMID 37015836 |
| Elinzanetant (NT-814), a Neurokinin 1,3 Receptor Antagonist, Reduces Estradiol and Progesterone in Healthy WomenThe Journal of clinical endocrinology and metabolism · 2021 | Human — controlled trial | Not recorded | — | The ideal therapy for endometriosis (EM) and uterine fibroids (UFs) would suppress estrogenic drive to the endometrium and myometrium, while minimizing vasomotor symptoms and bone loss associated with current treatments. An integrated neurokinin-kisspeptin system involving substance P and neurokinin B acting at the neurokinin (NK) receptors 1 and 3, respectively, modulates reproductive hormone secretion and represents a therapeutic target. This work aimed to assess the effect… | PMID 33624806 |
| Serum kisspeptin levels in polycystic ovary syndrome: A meta-analysisThe journal of obstetrics and gynaecology research · 2021 | Meta-analysis | Not recorded | — | To clarify the association of serum kisspeptin levels in women with polycystic ovary syndrome (PCOS) by meta-analysis. Two English databases and two Chinese databases were searched for the relationship between kisspeptin and PCOS published from 2009. After the studies screening according to specific principles, we used STATA 12.0 for meta-analysis. Standardized mean difference (SMD) and its 95% confidence intervals (95% CIs) were used as the effect size and STATA 12.0 softwar… | PMID 33765692 |
| Kisspeptin and its Current Clinical Status-A Systematic ReviewCurrent medicinal chemistry · 2025 | Systematic review | Not recorded | — | Kisspeptin was initially known as metastin for its role in suppressing metastasis in melanoma and breast cancer. Later, based on its ability to stimulate GPR54, its importance in maintaining an intact hypothalamic-pituitary-ovarian axis was recognised, which is the basis for the widespread application of the drug in several conditions such as secondary amenorrhea, regulation of puberty onset, ovarian function, trophoblast invasion, fertility regulation, parturition, and lacta… | PMID 38265397 |
Vendors listing Kisspeptin
The evidence above describes the published literature. What any individual vial contains is a separate question, answered by that vendor’s certificate records rather than by any study on this page.
| Vendor | Score · Coverage | Certificates | |
|---|---|---|---|
| Next Gen Peptides | 93.897% | 2 | profile → |
| PeptidePlugs | 89.790% | 2 | profile → |
| Hydro Research Peptides | 88.289% | 1 | profile → |
| American Peptides | 83.6100% | 1 | profile → |
| Northline Labs | 79.493% | 1 | profile → |
| NeuroLabs Research | 79.386% | 1 | profile → |
| Koi Peptides | 79.394% | 0 | profile → |
| Good Science Bio | 79.275% | 0 | profile → |
| Ascension Peptides | 78.186% | 1 | profile → |
| Licensed Peptides | 7789% | 1 | profile → |
| Modern Aminos | 74100% | 1 | profile → |
| GenX Peptides | 70.868% | 0 | profile → |
| Eternal Peptides | 68.265% | 0 | profile → |
| BioLongevity Labs | 67.274% | 0 | profile → |
| Mile High Compounds | 65.494% | 2 | profile → |
| Extreme Peptides | 64.282% | 1 | profile → |
How to read this page
This digest describes what published research exists and what it does not establish. It is not a recommendation, contains no dosing information or protocols, and makes no claim that any compound is safe or effective for any purpose. Material listed by indexed vendors is labeled for laboratory research use only.